Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
@article{205733,
author = {SHIVNATH SHINDE and Shrikrishna Baokar and swati burungale and Ashwini Pawar},
title = {ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF RAMIPRIL USING UV-VISIBLE SPECTROSCOPY: SINGLE POINT STANDARDIZATION, STANDARD ABSORPTIVITY, AND CALIBRATION CURVE APPROACH},
journal = {International Journal of Innovative Research in Technology},
year = {2026},
volume = {13},
number = {1},
pages = {7982-7988},
issn = {2349-6002},
url = {https://ijirt.org/article?manuscript=205733},
abstract = {UV spectrophotometric techniques play a crucial role in pharmaceutical analysis for the estimation of active compounds. This study presents the development and validation of a UV-Visible Spectroscopy method for Ramipril using methanol as a solvent. The method adheres to Beer-Lambert’s law and ICH guidelines, exhibiting a maximum absorbance at 207 nm. Excellent linearity (R² = 0.9992) was observed over the tested concentration range, with precise LOD and LOQ values confirming the method’s sensitivity. Additionally, the method demonstrated high precision, accuracy, and robustness, making it a reliable choice for routine pharmaceutical quality control applications.},
keywords = {UV spectrophotometry, Ramipril, Methanol, Validation, ICH, Pharmaceutical Analysis},
month = {June},
}
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