Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

@article{207154,
        author = {Rupali Gawande and Dr. Sarin Chavan and Ms. Nisha Varandani and Ms. Seema Kharwade and Ankita Sunil Gawande},
        title = {A Review on Kalanchoe pinnata Plant to Treat Urolithiasis},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {13},
        number = {2},
        pages = {4198-4206},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=207154},
        abstract = {Many therapeutic herbs have played a major role in supporting economic growth and accessible healthcare in India. One such herb that has been utilized for its medicinal qualities for thousands of years in India is Kalanchoe pinnata. It is frequently referred to as “Patharchatta.” It is a xerophytic shrub with fleshy, thick leaves. Kidney stones and urinary bladder stones are treated with its leaves. The antiurolithiatic action of Kalanchoe pinnata leaves has led to their selection in this study. After the extract was screened using phytochemicals, it was discovered to include saponins, phenolic compounds, and flavonoids. Two crucial assays, the crystal nucleation and aggregation assays, were used to examine the offered study project in vitro. Under in vitro circumstances, the inhibitory potential of the alcoholic extract of Kalanchoe pinnata was examined for the development of calcium oxalate crystals, which are primarily seen in the majority of kidney stones. Utilizing spectrophotometric techniques, the nucleation and aggregation of calcium oxalate crystals were measured independently. According to the results, Kalanchoe pinnata alcoholic extract has a greater ability to prevent crystal formation and aggregation. Kalanchoe pinnata has significant ability to dissolve calcium oxalate, the element most common in forming stones in the urinary tract, and also carries phytochemicals such as flavonoids, quercitrin, glycosides, carotenoids, saponin, kaempferol, and alkaloids that prevent CaOx crystal formation and deposition in renal tubules. The plant extract also reduces the size of calcium oxalate stones and has both treatment and preventive action in urolithiasis. Its pharmacological profile, including immunomodulator, CNS depressant, analgesic, antimicrobial, anti-inflammatory, antiallergic, antileishmanial, antitumor, antiulcer, antibacterial, antifungal, antihistamine, antiviral, febrifuge, gastroprotective, and anticancer activity, is reviewed and discussed. Currently a threatened species requiring conservation, the plant is simultaneously being investigated for its notable contributions to green chemistry.},
        keywords = {Kalanchoe pinnata; Pharmacognostical; Phytochemical; Pharmacological; Urolithiasis},
        month = {July},
        }