Mayuri V. Kalburge, Sangram U. Deshmukh, Nandkishor B. Bavage, Vidyasagar Gali, Shyamlila B. Bavage
Mechanism Of Resistance, Modes Of Action, Factors, Protein Synthesis
In this paper, to better understand the important phenomenon of antibiotic resistance, I shall begin by a review of antibiotics: their discovery, the history of their development, their modes of action, their clinical activities, and the factors determining response to therapy with antibiotics. I shall then investigate the mechanisms of antibiotic resistance, review some major epidemics due to antibiotic resistance and infectious diseases and antibiotic resistance. Antibiotics do not work all the time, their inappropriate use, nosocomal infections, and possible reservoirs of antibiotic resistant animal organisms causing human diseases will then lead us to an update on the present situation, highlighting the nanopore revolution in genomic sequencing of drug-resistant bacteria, precious nanometals, and look forward to the future of antibiotics.