Chloroquine and hydroxychloroquine as potential therapies against COVID-19

  • Unique Paper ID: 149343
  • Volume: 6
  • Issue: 12
  • PageNo: 15-19
  • Abstract:
  • The desperate search to find effective treatments for coronavirus disease 2019 (COVID-19), 2 generic drugs, used largely by rheumatologists and dermatologists to treat immune-mediated diseases, have entered the spotlight. The antimalarials hydroxychloroquine (HCQ) and chloroquine (CQ) have demonstrated antiviral activity against severe acute respiratory syndrome–coronavirus 2 (SARS–CoV-2) in vitro and in small, poorly controlled or uncontrolled clinical studies (1–3). Normally, such research would be deemed hypothesis-generating at best. Here, we try to provide guidance regarding clinical decision making both for patients with COVID-19 and those with immune-mediated conditions, such as systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA), and strategies to mitigate further harm to these patients.

Cite This Article

  • ISSN: 2349-6002
  • Volume: 6
  • Issue: 12
  • PageNo: 15-19

Chloroquine and hydroxychloroquine as potential therapies against COVID-19

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