FORMULATION AND DEVICE DESIGN TO INCREASE NOSE TO BRAIN DRUG DELIVERY SYSTEM

Megha S. Deshmukh; Khalid Shaikh; Nandkishor B. Bavage; Vidyasagar Gali; Shyamlila B. Bavage

FORMULATION AND DEVICE DESIGN TO INCREASE NOSE TO BRAIN DRUG DELIVERY SYSTEM

Authors: Megha S. Deshmukh, Khalid Shaikh, Nandkishor B. Bavage, Vidyasagar Gali, Shyamlila B. Bavage

Unique Paper ID: 149359
Volume: 6
Issue: 12
PageNo: 89-97

Keywords: Nose Nasal drug delivery systems Nose to Brain

Abstract:
Nasal drug delivery has received a great deal of attention as a convenient, reliable, and promising method for the systemic administration of drugs. The use of the nasal route for the delivery of challenging drugs such as small polar molecules, vaccines, hormones, peptides and proteins has created much interest in nowadays. It is especially for those molecules which are ineffective orally and only effective if administered by injection. Due to the high permeability, high vasculature, low enzymatic environment of nasal cavity and avoidance of hepatic first pass metabolism are well suitable for systemic delivery of drug molecule via nose. Many drug delivery devices for nasal application of liquid, semisolid and solid formulation are investigated to deliver the drugs to the treat most crisis CNS diseases (i.e., Parkinsonâ€™s disease, Alzheimerâ€™s disease) because it requires rapid and/or specific targeting of drugs to the brain. This review sets out to discuss some factors affecting nasal absorption, bio-availability barriers, strategies to improve nasal absorption, new developments in nasal dosage form design and applications of nasal drug delivery system.

Download article

email to a friend

Cite This Article

ISSN: 2349-6002
Volume: 6
Issue: 12
PageNo: 89-97

FORMULATION AND DEVICE DESIGN TO INCREASE NOSE TO BRAIN DRUG DELIVERY SYSTEM

Available:https://ijirt.org/Article?manuscript=149359

09 Nov, 2021

REVIEW ON DIABETES MELLITUS

17 Oct, 2021

DRUG REPURPOSING IN ANTIVIRAL RESEARCH: A REVIEW

08 Aug, 2021

RHINO-ORBITAL MUCORMYCOSIS ASSOCIATED WITH COVID-19

08 Aug, 2021

THE PRINCIPLES OF SKIN TISSUE ENGINEERING

08 Aug, 2021

A REVIEW ON LYME BORRELIOSIS

31 Jul, 2021

AWARENESS ABOUT BANNED DRUG

31 Jul, 2021

APPLICATION AND THE PRODUCTION OF RADIOPHARMACEUTICAL’S

30 Jul, 2021

ANTHELMINTIC ACTIVITY OF SOME MEDICINAL PLANTS

30 Jul, 2021

A REVIEW ON DRUMSTICK PLANTS (MORINGA OLEIFERA) MEDICAL USES AND NUTRITIONAL PROPERTIES

29 Jul, 2021

PHARMACOTHERAY OF HYPERTENSION

Impact Factor
8.01 (Year 2024)

UGC Approved
Journal no 47859

Join Our IPN

IJIRT Partner Network

Submit your research paper and those of your network (friends, colleagues, or peers) through your IPN account, and receive 800 INR for each paper that gets published.

Join Now

Latest Publication

Recent Conferences

NCSEM 2024

National Conference on Sustainable Engineering and Management - 2024 Last Date: 15th March 2024

Submit inquiry