ANTIMICROBIAL POTENTIAL OF NOVEL BENZOXAZINONE DERIVATIVES TETHERED WITH THIOSEMICARBAZONE SCAFFOLD

PRIYADARSHINI MANDRU; DR. PABBA PARAMESHWAR

ANTIMICROBIAL POTENTIAL OF NOVEL BENZOXAZINONE DERIVATIVES TETHERED WITH THIOSEMICARBAZONE SCAFFOLD

Authors: PRIYADARSHINI MANDRU, DR. PABBA PARAMESHWAR

Unique Paper ID: 160825
Volume: 8
Issue: 3
PageNo: 1141-1150

Keywords: No Keywords Found

Abstract:
Antibiotic resistance in bacterial pathogens has currently reached very high and alarming levels. Indeed, according to a number of international bodies, this â€œantibiotic resistance crisisâ€ could possibly bring us back to a â€œpre-antibiotic eraâ€ in the near future, if no effective actions are promptly undertaken [1,2]. Unfortunately, the low success rate in antimicrobial agentsâ€™ discovery and development observed during the last decades has led to a limited availability of new compounds for clinical use, thus exacerbating the burden of antibiotic resistance on morbidity and mortality rates. In this scenario, also many modern clinical practices associated with an increased risk of infection and in which antibiotics are essential (e.g., anti-cancer treatments, solid organ and stem cell transplantations, or implantation of prosthetic devices) are seriously at risk of success [3].

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ISSN: 2349-6002
Volume: 8
Issue: 3
PageNo: 1141-1150

ANTIMICROBIAL POTENTIAL OF NOVEL BENZOXAZINONE DERIVATIVES TETHERED WITH THIOSEMICARBAZONE SCAFFOLD

Available:https://ijirt.org/Article?manuscript=160825

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