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Formulation and evaluation of herbal toothpaste of murraya koenigii leaf extract

  • Unique Paper ID: 165892
  • Volume: 11
  • Issue: 1
  • PageNo: 2296-2306
  • Abstract:
  • The objective of this research was to determine the antibacterial activity of herbal toothpaste from the extract of Murraya koenigii leaves on Streptococcus mutans and Escherichia coli. Toothpaste was formulated with different concentrations of Murraya koenigii leaves, F1 extract (25 ppm), F2 (50 ppm), F3 (75 ppm) and F4 (100 ppm) on both aqueous extract by maceration and ethanolic extract Soxhlet extraction. Each formulation was tested the physical characteristics and antibacterial activity toward S. mutans and Escherichia coli to obtain the comparative study on aqueous and ethanolic extract potency of herbal toothpaste. Antibacterial activity was determined by Agar Well Diffusion method using mutans Hinton Mueller agar plates. Also, antibacterial activities were assessed by the presence or absence of inhibition zones after the plates were incubated at 37°C for 24 hours. The results of this test illustrated that all the toothpastes under study exhibited antibacterial activity at different concentrations of Murraya koenigii leaves. Antibacterial activity test showed maximum zone of inhibition by F4 (100 ppm) of ethanolic extract herbal toothpaste against Streptococcus mutans. The ethanolic extract herbal toothpaste shows better antibacterial action when compared to the aqueous extract. Therefore, these toothpastes can be used as natural antibacterial agents in preventing tooth decay caused by S. mutans and Escherichia coli. Toothpaste extracted from Murraya koenigii leaves of ethanolic extract showed significant antibacterial activity against S. mutans and E. coli in high concentration.
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  • ISSN: 2349-6002
  • Volume: 11
  • Issue: 1
  • PageNo: 2296-2306

Formulation and evaluation of herbal toothpaste of murraya koenigii leaf extract

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