Crystal structure of 4-(4-Bromo-phenoxymethyl)-5, 7-dimethyl-chromen-2-one (C18 H15 Br O3)

  • Unique Paper ID: 152611
  • Volume: 7
  • Issue: 4
  • PageNo: 383-386
  • Abstract:
  • 4-Phenoxymethylcoumarin was reported by by the reaction of 4-bromomethylcoumarin with phenol. Compound was subjected to the Claisen rearrangement at high temperature, which gave negative results Subsequently a number of 4-aryloxymethylcoumarins were synthesised as possible anti-microbial agents Introduction of biocompatible fragments like vanillin and paracetamol resulted in novel 4-aryloxymethylcoumarins and which exhibited anti-inflammatory, analgesic and interesting photophysical properties also. The first report on the X-ray diffraction studies on 4-aryloxymethylcoumarins has revealed that the molecules exist as head-tail dimers in solid state as observed in the case of 7-methyl-4-tolyloxymethylcoumarin In the light of above observations following 4-aryloxymethylcoumarins possessing chloro/bromo substituents have been subjected to X-ray diffraction studies.

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Copyright © 2025 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{152611,
        author = {Ramakrishna Gowda and Dr. K. V. Arjuna Gowda},
        title = {Crystal structure of  4-(4-Bromo-phenoxymethyl)-5, 7-dimethyl-chromen-2-one (C18 H15 Br O3)},
        journal = {International Journal of Innovative Research in Technology},
        year = {},
        volume = {7},
        number = {4},
        pages = {383-386},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=152611},
        abstract = {4-Phenoxymethylcoumarin was reported by by the reaction of 4-bromomethylcoumarin with phenol. Compound was subjected to the Claisen rearrangement at high temperature, which gave negative results  Subsequently a number of 4-aryloxymethylcoumarins were synthesised as possible anti-microbial agents Introduction of biocompatible fragments like vanillin and paracetamol resulted in novel 4-aryloxymethylcoumarins and which exhibited anti-inflammatory, analgesic and interesting photophysical properties also. The first report on the X-ray diffraction studies on 4-aryloxymethylcoumarins has revealed that the molecules exist as head-tail dimers in solid state as observed in the case of 7-methyl-4-tolyloxymethylcoumarin In the light of above observations following 4-aryloxymethylcoumarins possessing chloro/bromo substituents have been subjected to X-ray diffraction studies.},
        keywords = {Bromo, Dimethyl, crystal x-ray study, Molecular Packing and hydrogen bonding},
        month = {},
        }

Cite This Article

  • ISSN: 2349-6002
  • Volume: 7
  • Issue: 4
  • PageNo: 383-386

Crystal structure of 4-(4-Bromo-phenoxymethyl)-5, 7-dimethyl-chromen-2-one (C18 H15 Br O3)

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