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@article{167935,
        author = {Desale Roshani and Mirza Nazish Baig and TARANNUM SAMEER SATI and Chaitanya Pandit Chaudhari and Rutuja Anant Parte and Prachi Parashuram Sutar},
        title = {Role of Endophytic Fungi in the production of Bioactive plant metabolites},
        journal = {International Journal of Innovative Research in Technology},
        year = {2024},
        volume = {11},
        number = {4},
        pages = {866-873},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=167935},
        abstract = {Endophytic fungi, microorganisms that live symbiotically within plant tissues, have garnered significant attention for their ability to produce bioactive secondary metabolites. These compounds, including alkaloids, terpenoids, and flavonoids, play a crucial role in medicine, agriculture, and industry, offering immense potential for pharmaceutical applications. This review explores the biological and ecological characteristics of endophytic fungi, emphasizing their diversity, classification, and interactions with host plants. Key biosynthetic pathways are discussed, focusing on how these fungi contribute to the production of valuable plant metabolites. Case studies of fungi producing anticancer, antimicrobial, and immunomodulatory agents demonstrate their vast potential. Advanced methods for isolating, characterizing, and enhancing metabolite production, including metabolite profiling and genomic approaches, are examined. Additionally, the applications of endophytes in pharmaceuticals, agriculture, and industry are outlined, while addressing the technical challenges and research gaps that persist. This review emphasizes the need for continued research and technological innovations to fully unlock the potential of endophytic fungi in biotechnology.},
        keywords = {},
        month = {September},
        }