Vitamin B12 Deficiency In Older People A Practical Approach To Recognition And Management.

  • Unique Paper ID: 168960
  • Volume: 11
  • Issue: 6
  • PageNo: 102-110
  • Abstract:
  • Vitamin B12deficiency is common in older people and is linked to anaemia, cognitive decline, and dementia. Clinical presentation is variable, ranging from no symptoms or subtle, non-specific symptoms, through to serious, irreversible neurological symptoms if left untreated. Although common, it is often under-recognised, with diagnosis usually occurring on incidental blood test screening. Older people are at increased risk of vitamin B12deficiency due to insufficient dietary intake, malabsorption associated with aged-related changes in gastrointestinal function, higher incidence of pernicious anaemia, and chronic use of interfering medications such as metformin and proton-pump inhibitors. Early detection and treatment in symptomatic deficiency are crucial to prevent irreversible damage. Vitamin B12intramuscular injection bypasses potential absorption issues and is traditionally the first-line treatment in older people. However, emerging evidence suggests that high-dose oral replacement may be as effective.

Copyright & License

Copyright © 2025 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{168960,
        author = {Sandhya  Sujeetkumar Ahire and SUJEETKUMAR I.AHIRE and Chetan S.Chaudhari and Vaibhav L. Chaudhari},
        title = {Vitamin B12 Deficiency In Older People A Practical Approach To Recognition And Management.},
        journal = {International Journal of Innovative Research in Technology},
        year = {2024},
        volume = {11},
        number = {6},
        pages = {102-110},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=168960},
        abstract = {Vitamin B12deficiency is common in older people and is linked to anaemia, cognitive decline, and dementia. Clinical presentation is variable, ranging from no symptoms or subtle, non-specific symptoms, through to serious, irreversible neurological symptoms if left untreated.
Although common, it is often under-recognised, with diagnosis usually occurring on incidental blood test screening. Older people are at increased risk of vitamin B12deficiency due to insufficient dietary intake, malabsorption associated with aged-related changes in gastrointestinal function, higher incidence of pernicious anaemia, and chronic use of interfering medications such as metformin and proton-pump inhibitors. Early detection and treatment in symptomatic deficiency are crucial to prevent irreversible damage.
Vitamin B12intramuscular injection bypasses potential absorption issues and is traditionally the first-line treatment in older people. However, emerging evidence suggests that high-dose oral replacement may be as effective.},
        keywords = {Vitamin B12, deficiency, anaemia, malabsorption, neurological symptoms},
        month = {November},
        }

Cite This Article

  • ISSN: 2349-6002
  • Volume: 11
  • Issue: 6
  • PageNo: 102-110

Vitamin B12 Deficiency In Older People A Practical Approach To Recognition And Management.

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