Vitamin B12 Deficiency In Older People A Practical Approach To Recognition And Management.

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Sandhya  Sujeetkumar Ahire; SUJEETKUMAR I.AHIRE; Chetan S.Chaudhari; Vaibhav L. Chaudhari

Vitamin B12 Deficiency In Older People A Practical Approach To Recognition And Management.

Authors: Sandhya Sujeetkumar Ahire, SUJEETKUMAR I.AHIRE, Chetan S.Chaudhari, Vaibhav L. Chaudhari

Unique Paper ID: 168960
Volume: 11
Issue: 6
PageNo: 102-110

Keywords: Vitamin B12 deficiency anaemia malabsorption neurological symptoms

Abstract:
Vitamin B12deficiency is common in older people and is linked to anaemia, cognitive decline, and dementia. Clinical presentation is variable, ranging from no symptoms or subtle, non-specific symptoms, through to serious, irreversible neurological symptoms if left untreated. Although common, it is often under-recognised, with diagnosis usually occurring on incidental blood test screening. Older people are at increased risk of vitamin B12deficiency due to insufficient dietary intake, malabsorption associated with aged-related changes in gastrointestinal function, higher incidence of pernicious anaemia, and chronic use of interfering medications such as metformin and proton-pump inhibitors. Early detection and treatment in symptomatic deficiency are crucial to prevent irreversible damage. Vitamin B12intramuscular injection bypasses potential absorption issues and is traditionally the first-line treatment in older people. However, emerging evidence suggests that high-dose oral replacement may be as effective.

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ISSN: 2349-6002
Volume: 11
Issue: 6
PageNo: 102-110

Vitamin B12 Deficiency In Older People A Practical Approach To Recognition And Management.

Available:https://ijirt.org/article?manuscript=168960

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