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@article{172494, author = {vinod kumar and Uday Mishra and Chandra Kant and Jaynath Kumar and Ram kumar and Rajesh kumar and Saheban Khan and Nitesh kumar}, title = {Synthesis and Application of C-5'-triazolyl-nucleosides}, journal = {International Journal of Innovative Research in Technology}, year = {2025}, volume = {11}, number = {9}, pages = {861-868}, issn = {2349-6002}, url = {https://ijirt.org/article?manuscript=172494}, abstract = {Modified nucleosides are the core precursor nucleic acid, and it has a significant contribution medicinal chemistry and drug discovery. So that, prepare different triazolyl scaffolds, ruthenium and copper catalysed azide-alkyne 1,3-dipolar cycloaddition reactions also known as click reaction have developed as a facile and efficient unique tool because of its simplicity and ideal conditions. Introduction of a triazole ring in nucleosides, improves their therapeutic value and different photophysical attributes. In this article, discussed the synthesis and application of C-5’-triazolyl nucleosides.}, keywords = {Triazole, nucleoside, click chemistry, anti-cancer, anti-viral.}, month = {February}, }
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