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@article{173164, author = {Dr. Pranjali Baliram Kharat and Dr. Sneha Shyamkant Bhokare and Dr. Sangeeta Gorakshnath Kanade and Dr. Surekha Babasaheb Khandekar}, title = {EXPLORING THE DUAL NATURE OF DHATURA: THERAPEUTIC USES AND TOXICITY IN AYURVEDA}, journal = {International Journal of Innovative Research in Technology}, year = {2025}, volume = {11}, number = {9}, pages = {2619-2621}, issn = {2349-6002}, url = {https://ijirt.org/article?manuscript=173164}, abstract = {Dhatura (Datura metel) is a plant of significant importance in Ayurveda, particularly within the branch of Agad Tantra, which focuses on the identification and treatment of poisons. Known for both its medicinal properties and toxic effects, Dhatura contains alkaloids such as atropine, hyoscyamine, and scopolamine, which contribute to its pharmacological actions, including analgesic, anti-inflammatory, anti-asthmatic, and wound-healing effects. However, improper use of Dhatura can lead to poisoning, manifesting symptoms like confusion, hallucinations, delirium, and even death in extreme cases. In Ayurveda, Dhatura is classified as an Upavisha (mild poison) and is used in various formulations for treating ailments like asthma, cough, fever, inflammation, and neuralgia. The plant is also employed in formulations for conditions like amlapitta (acid dyspepsia), shwasa (asthma), and krimi (parasitic infections). Despite its therapeutic potential, the toxicological profile of Dhatura makes it a dangerous substance if consumed improperly. Accidental poisoning is common, especially from the seeds, which are often mistaken for edible seeds. The toxic effects of Dhatura include dryness of the mouth, dilated pupils, delirium, and hyperpyrexia. Ayurvedic antidotes such as cow milk with sugar, Vrintaka fruit juice, and Nimbu Swarasa are recommended for managing toxicity. This article provides an overview of the dual nature of Dhatura, emphasizing the need for caution and expert knowledge in its application for therapeutic purposes within Agad Tantra and Ayurveda.}, keywords = {Agad Tantra, Dhatura, medicinal properties, poisoning, toxicity, Upavisha.}, month = {February}, }
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