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@article{183369,
        author = {Mr. Aadesh A. Nalawade and Mr. Siddharth S. Kale and Mr. Omkar C. Jadhav and Mr. Abhishek P. Bhor},
        title = {FORMULATION AND EVALUATION OF FLOATING TABLETS OF CIPROFLOXACIN HYDROCHLORIDE},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {12},
        number = {3},
        pages = {1155-1162},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=183369},
        abstract = {The present study focuses on the formulation and evaluation of floating tablets containing Ciprofloxacin Hydrochloride, developed via direct compression technique. Various concentrations of Mimosa gum were employed as a natural polymeric matrix, while citric acid acted as a stabilizer and sodium bicarbonate served as the effervescent agent to facilitate buoyancy. Magnesium stearate and lactose were incorporated as lubricants and diluents, respectively. Each formulation underwent thorough assessment of both pre-compression and post-compression parameters to ensure optimal tablet characteristics. In vitro dissolution studies revealed that Formulation F4 demonstrated a drug release of 68.70% within 6 hours, indicating efficient and sustained drug delivery. Based on its performance, Formulation F4 holds strong potential for further advancement through bioavailability studies, pharmacokinetic profiling, and in vivo evaluations, positioning it as a promising candidate for novel gastro-retentive drug delivery systems.},
        keywords = {Ciprofloxacin Hydrochloride, floating tablet, mimosa gum, floating lag time, in vitro drug release.},
        month = {August},
        }