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@article{187813,
        author = {Saundarya D. Rajput and Diksha Narwade},
        title = {Development of a Herbal Mouthwash containing Mimosa pudica and Egg Albumin for Tannin Reduction},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {12},
        number = {6},
        pages = {6248-6256},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=187813},
        abstract = {The development of effective, natural oral-care formulations has gained increasing attention due to growing concerns over the adverse effects and synthetic nature of conventional mouthwashes. This review article explores the formulation and therapeutic potential of a herbal mouthwash incorporating Mimosa pudica extract and egg albumin, aimed specifically at reducing tannin-related oral issues. Mimosa pudica, a well-known medicinal plant rich in bioactive compounds, exhibits antimicrobial, anti-inflammatory, and antioxidant properties that contribute to improved oral hygiene. Egg albumin, on the other hand, possesses excellent protein-binding capabilities, enabling it to interact with tannins and potentially neutralize their astringent and enamel-staining effects. The review summarizes existing literature on the phytochemical constituents of Mimosa pudica, its mechanism of action in oral health, and the scientific basis for tannin complexation by albumin proteins. It further discusses formulation considerations such as extract standardization, pH optimization, stability, and synergistic interactions between plant constituents and albumin. Additionally, the article highlights in-vitro studies assessing antimicrobial activity, tannin-binding efficiency, and biocompatibility of the herbal mouthwash, while also identifying gaps in current research that warrant further investigation, including long-term clinical efficacy and sensory acceptability. Overall, this review underscores the potential of combining botanical extracts with natural proteins to develop an effective, safe, and eco-friendly oral hygiene product. The integration of Mimosa pudica and egg albumin represents a promising strategy for managing tannin-related discoloration and oral discomfort, offering a novel alternative to commercially available chemical mouthwashes. Through a comprehensive evaluation of existing evidence, this article provides a foundation for future research and innovation in herbal dental formulations.},
        keywords = {Mimosa pudica; egg albumin; herbal mouthwash; tannin reduction; phytochemicals; oral hygiene; protein–tannin interaction; natural formulations.},
        month = {November},
        }