Synthesis of Novel Aromatic Compounds via Schiff Base Method: Advances, Applications, and Future Perspectives

  • Unique Paper ID: 194516
  • Volume: 12
  • Issue: 10
  • PageNo: 4363-4371
  • Abstract:
  • Schiff bases represent an important class of organic compounds characterized by the presence of an azomethine (–C=N–) functional group formed through condensation between primary amines and carbonyl compounds. Aromatic Schiff bases have attracted considerable attention due to their structural diversity, facile synthesis, and wide range of biological and industrial applications. Recent developments focus on designing novel aromatic compounds with enhanced pharmacological, catalytic, and material properties. This review highlights synthetic strategies, reaction mechanisms, characterization techniques, biological activities, and emerging applications of Schiff base–derived aromatic compounds. Special emphasis is placed on green synthesis approaches and medicinal chemistry advancements.

Copyright & License

Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{194516,
        author = {Mohite Vaishnavi Sitaram and Tidke Poonam Namdeo},
        title = {Synthesis of Novel Aromatic Compounds via Schiff Base Method: Advances, Applications, and Future Perspectives},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {10},
        pages = {4363-4371},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=194516},
        abstract = {Schiff bases represent an important class of organic compounds characterized by the presence of an azomethine (–C=N–) functional group formed through condensation between primary amines and carbonyl compounds. Aromatic Schiff bases have attracted considerable attention due to their structural diversity, facile synthesis, and wide range of biological and industrial applications. Recent developments focus on designing novel aromatic compounds with enhanced pharmacological, catalytic, and material properties. This review highlights synthetic strategies, reaction mechanisms, characterization techniques, biological activities, and emerging applications of Schiff base–derived aromatic compounds. Special emphasis is placed on green synthesis approaches and medicinal chemistry advancements.},
        keywords = {Schiff base, aromatic compounds, azomethine, condensation reaction, medicinal chemistry, green synthesis.},
        month = {March},
        }

Cite This Article

Sitaram, M. V., & Namdeo, T. P. (2026). Synthesis of Novel Aromatic Compounds via Schiff Base Method: Advances, Applications, and Future Perspectives. International Journal of Innovative Research in Technology (IJIRT), 12(10), 4363–4371.

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