Formulation Development And Characterization Of Novel Antipsoriatic Gel For Topical Drug Delivery Sysyem.

  • Unique Paper ID: 194860
  • Volume: 12
  • Issue: 10
  • PageNo: 6384-6396
  • Abstract:
  • Studies using FTIR spectroscopy verified that the medicine and excipients are compatible. Dimethyl sulfoxide, Carbopol 10NF, propylene glycol, glycerol, methyl paraben, propyl paraben, and water were used to make the gel. Out of all the formulations, the Optimized formulation (F3) is the most effective. The prepared gel demonstrated satisfactory physical characteristics, including assay (97%w/w) and pH (4.99). Additionally, 98.2% of the medication was released in 12 hours according to in vitro diffusion experiments. For one, two, and three months, the formulation was loaded for stability at accelerated conditions of 40°C/75%RH and 30°C/65%RH. The optimized formulation (F3) has demonstrated satisfactory in vitro performance and good stability.

Copyright & License

Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{194860,
        author = {Prajkta Diwakar Durge and Dr. P.M. Pimpalshende},
        title = {Formulation Development And Characterization Of Novel Antipsoriatic Gel For Topical Drug Delivery Sysyem.},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {10},
        pages = {6384-6396},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=194860},
        abstract = {Studies using FTIR spectroscopy verified that the medicine and excipients are compatible. Dimethyl sulfoxide, Carbopol 10NF, propylene glycol, glycerol, methyl paraben, propyl paraben, and water were used to make the gel. Out of all the formulations, the Optimized formulation (F3) is the most effective. The prepared gel demonstrated satisfactory physical characteristics, including assay (97%w/w) and pH (4.99). Additionally, 98.2% of the medication was released in 12 hours according to in vitro diffusion experiments. For one, two, and three months, the formulation was loaded for stability at accelerated conditions of 40°C/75%RH and 30°C/65%RH. The optimized formulation (F3) has demonstrated satisfactory in vitro performance and good stability.},
        keywords = {},
        month = {March},
        }

Cite This Article

Durge, P. D., & Pimpalshende, D. P. (2026). Formulation Development And Characterization Of Novel Antipsoriatic Gel For Topical Drug Delivery Sysyem.. International Journal of Innovative Research in Technology (IJIRT), 12(10), 6384–6396.

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