Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

@article{206732,
        author = {Kamaljit kaur and Anjali Dixit and Jyotika Rani and Shruti Sharma and Sanjana Piplani},
        title = {Formulation and Evaluation of Topical Antifungal Nanogel of Moringa oleifera and Nyctanthes arbor-tristis},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {13},
        number = {2},
        pages = {2597-2606},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=206732},
        abstract = {Moringa oleifera and Nyctanthes arbor-tristis are medicinal plants widely recognized for their potent antifungal, anti-inflammatory, antioxidant, and wound-healing properties owing to their rich phytochemical constituents, including flavonoids, phenolics, alkaloids, and glycosides. The present study aimed to develop a herbal-loaded nanogel incorporating combined extracts of these plants for topical antifungal therapy. Six formulations (F1–F6) were prepared and evaluated for physicochemical properties, drug release, and release kinetics. Among them, F4 exhibited optimum pH, viscosity, spreadability, extrudability, drug content, and sustained drug release following the Higuchi diffusion model with non-Fickian transport. The optimized nanogel demonstrated favorable particle characteristics, significant antifungal activity against Aspergillus niger, and excellent stability, indicating its potential as a safe and effective topical herbal drug delivery system.},
        keywords = {Antifungal, Moringa oleifera, Nyctanthes arbor-tristis, formulationsAntifungal, Moringa oleifera, Nyctanthes arbor-tristis, formulations},
        month = {July},
        }