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@article{168086, author = {Mr. Gite Krushna Shivram and Mr. Mohammad Zishan Ibrahim and Dr. Jameel Ahmad}, title = {Human Serum Albumin: A Novel Drug Delivery Carrier System}, journal = {International Journal of Innovative Research in Technology}, year = {2024}, volume = {11}, number = {4}, pages = {1281-1286}, issn = {2349-6002}, url = {https://ijirt.org/article?manuscript=168086}, abstract = {With the success of several clinical trials of products based on human serum albumin (HAS) and the rapid developments of nanotechnology, HAS-based Nano-drug delivery systems (HBNDSs) have received Extensive attention in the field of nano-medicine. However, there is still a lack of comprehensive reviews exploring the broader scope of HBNDSs in biomedical applications beyond cancer therapy. To address this gap, this review takes a systematic approach. Firstly, it focuses on the crystal structure and the potential binding sites of HAS. Additionally, it provides a comprehensive summary of recent progresses In the field of HBNDSs for various biomedical applications over the past five years, categorized according To the type of therapeutic drugs loaded onto HAS. These categories include small-molecule drugs, inorganic Materials and bioactive ingredients. Finally, the review summarizes the characteristics and current Application status of HBNDSs in drug delivery, and also discusses the challenges that need to be addressed for the clinical transformation of HS.}, keywords = {human serum albumin as drug delivery, biomedical applications of albumin}, month = {September}, }
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