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@article{186765,
        author = {Mrunali D. Shrirame and Dr. S. N. Wani and Md Quamruz Zafar},
        title = {Endocrine Regulation of Hair Growth and Loss: Current Evidence and Clinical Implications},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {12},
        number = {6},
        pages = {2044-2049},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=186765},
        abstract = {Hair growth and loss are intricately regulated by endocrine factors that influence follicular cycling, differentiation, and regeneration. Hormones such as androgens, estrogens, thyroid hormones, prolactin, insulin, and cortisol play pivotal roles in modulating hair follicle activity, with imbalances contributing to various forms of alopecia, including androgenetic, thyroid-related, and estrogen-deficiency–associated types. This narrative review synthesizes current evidence on the endocrine regulation of hair growth, highlighting the molecular mechanisms through which hormones exert their effects and their clinical implications in diagnosing and managing endocrine-mediated hair disorders. It emphasizes the importance of gender-specific management, hormonal assessment in alopecia evaluation, patient counseling, and multidisciplinary collaboration between dermatology and endocrinology. Despite notable advances, substantial research gaps remain, particularly in standardized evaluation methods, long-term clinical trials, and female-focused investigations. Future directions point toward omics-based profiling, personalized endocrine modulation, regenerative therapies, and combination treatment strategies to develop more effective and durable solutions. A deeper understanding of hormonal influences on hair biology may ultimately enable tailored, mechanism-driven therapies for diverse endocrine-related alopecias.},
        keywords = {Endocrine regulation, Hair loss, Alopecia, Hormonal imbalance, Androgens, Estrogen, Thyroid hormones, Personalized medicine},
        month = {November},
        }