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@article{201670,
        author = {Ms. Mangnale Mayuri Mamath and Mr. Gavhane Sandeepan Dnyanoba and . Suryavanshi Anagha A. and Ms. Shinde Sangita Shiwaji and Ms. Kendre Aishwariya Dattatry and Mr. Mohammad Zishan Ibrahim},
        title = {FORMULATION AND EVALUATION OF HERBAL GEL FOR SKIN INFECTION},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {12},
        pages = {5167-5173},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=201670},
        abstract = {Hydrogels are three-dimensional hydrophilic polymeric networks capable of absorbing and retaining large amounts of water while maintaining structural integrity. The present study focuses on the development and evaluation of a poly-herbal hydrogel for topical drug delivery using natural ingredients such as Aloe vera, papaya extract, and clove oil. These herbal components were selected due to their well-known antimicrobial, anti-inflammatory, antioxidant, and wound-healing properties. The hydrogel was formulated using Carbopol 934 as a gelling agent, along with suitable excipients including propylene glycol, methyl paraben, and triethanolamine.
The prepared formulation was evaluated for various physicochemical parameters such as physical appearance, pH, viscosity, spread ability, swelling index, content uniformity, in-vitro drug release, syneresis, and stability. The results indicated that the hydrogel was smooth, homogeneous, and exhibited good consistency with a skin-compatible pH. The formulation showed appropriate viscosity, good spread ability, and excellent swelling behavior, which are essential for effective topical application. In-vitro drug release studies demonstrated a sustained release pattern, indicating controlled delivery of active constituents.
The absence of syneresis and stability issues confirmed the robustness of the formulation. Overall, the developed poly-herbal hydrogel demonstrated satisfactory physicochemical properties and therapeutic potential, suggesting its suitability as an effective and safe alternative for topical drug delivery systems.},
        keywords = {},
        month = {May},
        }