Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

@article{206430,
        author = {Sruthi Maktala},
        title = {ANALGESIC ACTIVITY OF ETHANOLIC EXTRACT OF OCIMUM SPECIES IN FROGS},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {13},
        number = {2},
        pages = {1963-1966},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=206430},
        abstract = {The present investigation evaluated the analgesic potential of ethanolic extract of Ocimum basilicum using Rana tigrina as an experimental model. Herbal medicines are widely explored because of their comparatively lower adverse effects and traditional therapeutic importance. In this study, frogs were selected as a simple and economical experimental model to assess pain modulation through behavioural parameters such as eye blinking and buccal oscillations. Ethanolic extract of Ocimum basilicum was administered in different doses and compared with paracetamol as the standard analgesic drug. The extract demonstrated a significant reduction in eye blinking and buccal oscillations after induction of pain using sodium chloride solution, indicating analgesic activity. The findings support the traditional medicinal use of Ocimum species and suggest that flavonoids, phenolic compounds, and volatile oils present in the extract may contribute to pain inhibition. The study highlights the importance of medicinal plants as potential alternatives for pain management and encourages further pharmacological investigations.},
        keywords = {},
        month = {July},
        }