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@article{149343, author = {Yewange Sangmeshwar and Deshpande Renuka and Nikhil Waghmare and Vidyasagar Gali and Shyamlila B. Bavage and Nandkishor B. Bavage}, title = {Chloroquine and hydroxychloroquine as potential therapies against COVID-19}, journal = {International Journal of Innovative Research in Technology}, year = {}, volume = {6}, number = {12}, pages = {15-19}, issn = {2349-6002}, url = {https://ijirt.org/article?manuscript=149343}, abstract = {The desperate search to find effective treatments for coronavirus disease 2019 (COVID-19), 2 generic drugs, used largely by rheumatologists and dermatologists to treat immune-mediated diseases, have entered the spotlight. The antimalarials hydroxychloroquine (HCQ) and chloroquine (CQ) have demonstrated antiviral activity against severe acute respiratory syndrome–coronavirus 2 (SARS–CoV-2) in vitro and in small, poorly controlled or uncontrolled clinical studies (1–3). Normally, such research would be deemed hypothesis-generating at best. Here, we try to provide guidance regarding clinical decision making both for patients with COVID-19 and those with immune-mediated conditions, such as systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA), and strategies to mitigate further harm to these patients.}, keywords = {chloroquine clinical research clinical trials corona virus in COVID-19 disease & medicine hydroxychloroquine malaria nut shell SARS-CoV-2}, month = {}, }
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