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@article{192202,
        author = {HUMA JATIL and Dr. Reetesh yadav and Dr Deepak Patel and Dr Pankaj Tiwari and Mr Dilend Patle},
        title = {DESIGN AND SYNTHESIS OF POTENTIAL ANTI- INFLAMMATORY AGENTS},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {9},
        pages = {665-672},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=192202},
        abstract = {Inflammation is a complex biological response involved in the pathogenesis of various acute and chronic disorders. The limitations associated with currently available anti-inflammatory drugs, including adverse effects and reduced efficacy upon prolonged use, necessitate the development of safer and more effective therapeutic agents. In the present study, a series of novel compounds were rationally designed and synthesized as potential anti-inflammatory agents based on structure–activity relationship considerations.
The synthesized compounds were obtained using conventional organic synthetic methodologies and characterized by spectroscopic techniques such as FT-IR, ^1H NMR, ^13C NMR, and mass spectrometry. The anti-inflammatory activity of the prepared compounds was evaluated using standard in vivo and/or in vitro models, and the results were compared with those of standard reference drugs. Several compounds demonstrated significant anti-inflammatory activity, indicating that appropriate structural modifications play a crucial role in enhancing biological efficacy. The findings suggest that these newly designed molecules may serve as promising lead candidates for further optimization in the development of novel anti-inflammatory drugs.},
        keywords = {Anti-inflammatory agents; Drug design; Synthesis; Structure–activity relationship; Spectral characterization; Biological evaluation},
        month = {February},
        }