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@article{201709,
        author = {Ms. Kendre Aishwariya Dattatry and Mr. Gavhane Sandeepan Dnyanoba and Ms. Suryavanshi Anagha A. and Ms. Mangnale Mayuri Mamath and Ms. Shinde Sangita Shiwaji and Mr. Mohammad Zishan Ibrahim},
        title = {FORMULATION AND EVALUATION OF MOUTH WASH USING GUAVA LEAVES FOR APHTHOUS ULCER TREATMENT},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {12},
        pages = {10553-10565},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=201709},
        abstract = {Aphthous ulcers, commonly known as canker sores, are painful ulcerative lesions affecting the oral mucosa and are frequently associated with inflammation, microbial infection, nutritional deficiency, stress, and immune disturbances. Conventional treatment approaches mainly include corticosteroids, antiseptic mouthwashes, and analgesic preparations; however, prolonged use of synthetic agents may cause adverse effects such as staining of teeth, altered taste sensation, and mucosal irritation. Herbal formulations have emerged as safer and economical alternatives due to their therapeutic efficacy and minimal side effects. Guava leaves (Psidium guajava) possess significant antimicrobial, anti-inflammatory, antioxidant, and wound healing properties because of the presence of flavonoids, tannins, triterpenoids, and phenolic compounds. The present research focuses on the formulation and evaluation of herbal mouthwash prepared using guava leaf extract for the management of aphthous ulcers. The prepared formulation was evaluated for organoleptic properties, pH, viscosity, stability, antimicrobial activity, and ulcer healing potential. The results demonstrated that guava leaf mouthwash showed good stability, acceptable physicochemical characteristics, and promising antimicrobial activity against oral pathogens. The herbal mouthwash also exhibited potential in reducing pain, inflammation, and ulcer size. Thus, guava leaf-based mouthwash can be considered a safe and effective herbal alternative for the treatment of aphthous ulcers. 
A clinical study published in the Philippine Journal of Otolaryngology Head and Neck Surgery reported that guava leaf mouthwash significantly reduced pain and accelerated healing of aphthous ulcers compared with saline mouthwash.},
        keywords = {},
        month = {May},
        }