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@article{187421,
        author = {Miss. Vaishnavi M. Wagh and Miss. Nikita P.Pawar and Miss. Pooja Bhosale},
        title = {SELF-MICROEMULSIFYING DRUG DELIVERY SYSTEM},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {12},
        number = {6},
        pages = {4264-4272},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=187421},
        abstract = {In many conditions, the oral route is the most practical approach to provide medication, and it is still the first method being researched when novel dosage forms are being developed. Low and inconsistent bioavailability, which is primarily caused by poor water solubility, is the fundamental issue with oral medication formulations. Poor water solubility affects around 40% of prospective pharmaceutical medicines. Lipid-based formulations are gaining popularity for the therapeutic administration of lipophilic active moieties (Class II medicines in the biopharmaceutical classification system). The poor solubility, dissolving rate, and bioavailability of insoluble pharmaceuticals can now be addressed by a variety of technologies. Self-microemulsifying drug delivery systems (SMEDDS) are a promising method. Due to their capacity to improve the solubility and bioavailability of poorly soluble medications, SMEDDS have become more well-known. Formulations to enhance the oral absorption of extremely lipophilic medicinal molecules can be designed using SMEDDS, which are isotropic combinations of oils, surfactants, solvents, and co-solvents/surfactants. The majority of conventional SMEDDS are made in liquid form, which has certain drawbacks. SMEDDS can create fine, reasonably stable oil-in-water emulsions can be taken orally in soft or hard gelatin capsules. Solid-SMEDDS, which have grown in popularity, are made by solidifying liquid or semisolid self-micron emulsifying materials into powders. This page provides a thorough review of SMEDDS; nonetheless, the concept, design, and assessment of SMEDDS have received more attention than its use.},
        keywords = {Self-microemulsifying drug delivery system, Surfactant, Oil, Co-surfactant, Bioavailability, Lipophilic, Biopharmaceutical classification system Class II drugs.},
        month = {November},
        }